Are Brain Natriuretic Peptide Levels, High-sensitivity Troponin T Assay and Certain Left Atrial Echocardiographic Parameters Useful in the Evaluation of Patients with Permanent Pacemakers?

ORIGINAL RESEARCH, September 2014, VOL III ISSUE I, ISSN 2042-4884
10.5083/ejcm.20424884.121 , Cite or Link Using DOI
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Janusz Sielski MD PhD, Urszula Grabowska MD PhD

ABSTRACT

Background:

The present study was undertaken to evaluate the practical value of BNP measurements, high-sensitivity troponinT (TnT hs) assay and echocardiographic left ventricular volume index (LAVI) in patients with permanent pacemakers, as there are no such reports in the literature.

Methods and Results:
BNP measurements were performed on venous blood samples using the Triage meters. The “sandwich” test was used to assess TnT hs assay. The Simpson method and the ellipse method were used to assess the left atrium on echocardiography.

In the group II BNP levels, TnT hs levels increased. LAVI decreased. The probability of survival was higher in patients with low BNP before implantation.

Conclusions:
1. Measurements of BNP, TnT hs and LAVI provide new information regarding cardiovascular changes after pacemaker implantation and contribute to improvement of post-implant checkups.
2. Measurements of BNP, TnT hs and LAVI in patients with permanent pacemakers facilitate the assessment of survival and cardiovascular hospitalisation rate.