Evaluating the association between RDW values and mortality in patients suffering from heart failure

Vol V Issue VI
10.5083ejcm20424884.167 , Cite or Link Using DOI
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Behnemoon M; Koushkzari M

Aim: we aimed to determine the association between Reticulocyte Distribution Width (RDW) values and hemoglobin (Hb) levels with one- year mortality in patients suffering from heart failure (HF). Methods: In this retrospective study, all patients, who were hospitalized at the cardiology ward of ShahidTaleghani General Hospital, Urmia, Iran, from March 2015 to February 2016 with the diagnosis of HF, were enrolled. Blood samples were obtained from all the patients at the time of admission for hemoglobin, RDW, lipid profile, renal and liver function tests and blood sugar estimation. Details of ejection fraction, sex, age, comorbidities (coronary artery disease, hypertension, diabetes mellitus, hyperlipidemia and smoking) were extracted from the hospital records and the discharge summary of these patients. Also, all patients were followed up for 12 months via telephone calls or follow-up out- patient clinic or hospital visits. Significance was set at P-value <0.05. Results: Our findings revealed that a meaningful association was only present between high blood pressure and RDW (P=0.03). No significant association was seen between RDW and hemoglobin with underlying diseases. Total 68 (79.1%) of the patients with high RDW and 155 (89.6%) of those with normal RDW values survived through the follow-up period, and this difference was statistically significant (p=0.03). Data analysis revealed that the average survival of patients with RDW >14.4 and <14.4 was 10±4.37 and 11.16±0.19 months, respectively (p=0.017). Conclusion: Our study shows an association between RDW and one-year mortality in patients suffering from heart failure. It can be concluded that RDW, which is routinely