Optimisation of New Generation Endo-coronary Fourier Domain Optical Coherence Tomography

ORIGINAL RESEARCH, May 2013, VOL II ISSUE III, ISSN 2042-4884
10.5083/ejcm.20424884.94 , Cite or Link Using DOI
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Righab Hamdan MD, Saiid Ghostine MD, Nicolas Amabile MD, Christiophe Caussin MD

ABSTRACT:


Background and aim: Fourier domain Optical Coherence Tomography is a new imaging modalitycharacterised by a high resolution (10 -15) μm. We aimed to optimise this technique by determining the optimal flushing solution, the optimal pull-back speed, and the optimal injection rate and volume regimen.

Materials and methods: Animal model: We performed FD-OCT on a swine model. We tested multiple flushing solutions at 2 injection rate and volume regimens.
Results: Half strength Iodixanol/ voluven solution yielded excellent image quality comparable to the full strength Iodixanol.

Conclusion: Half strength Iodixanol/ voluven solution seems to be an efficient alternative to full strength Iodixanol with an acquisition quality comparable and with half the usual dose of contrast agent.