The impact of coronary artery disease on early outcome of aortic valve replacement in elderly patients

10.5083/ejcm.20424884.134 , Cite or Link Using DOI
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Seyed Yaser Hariri MD, Reza Arefizadeh MD, Raheleh Mousavi MD


The operative risk of aortic valve replacement (AVR) depends on several factors such as underlying coronary artery disease (CAD).

Objective: The aim of this study was to determine postoperative complications and early outcome for elderly patients with CAD undergoing isolated aortic valve replacement and compare them with patients without CAD.

Methods: Preoperative characteristics, postoperative in-hospital complications, 30-day mortality rate, and length of stay in hospital (LOS) in 79 patients at least 65 years old that underwent isolated AVR (53 patients with CAD and 25 patients without CAD) were studied and compared.

All studied in-hospital complications were similar between the two groups. No significant difference in 30-day mortality rate between the two groups was found (CAD group 8.1%, non CAD group 10.0%, P=0.781), whereas the mean of ICU stay in patients with CAD was higher than other patients (75.9 versus 47.6 hours, P=0.006). Female gender, obesity, hypertension, prolonged ventilation, and postoperative heart block in patients with CAD and only obesity in other group were significant predictors of 30-day mortality.

Conclusion: Early outcome of patients with and without CAD undergoing aortic valve replacement was similar.